Alex Bobik Selected Research

Immunoglobulins (Immunoglobulin)

1/2021	Alarmin-activated B cells accelerate murine atherosclerosis after myocardial infarction via plasma cell-immunoglobulin-dependent mechanisms.
1/2019	B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis.
1/2018	Follicular B Cells Promote Atherosclerosis via T Cell-Mediated Differentiation Into Plasma Cells and Secreting Pathogenic Immunoglobulin G.

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Alex Bobik Research Topics

Disease

34	Atherosclerosis 01/2023 - 12/2002
14	Inflammation (Inflammations) 01/2023 - 12/2003
10	Atherosclerotic Plaque (Atheroma) 01/2022 - 02/2004
8	Myocardial Infarction 01/2021 - 08/2003
7	Neointima 05/2009 - 06/2002
5	Rupture 01/2022 - 01/2002
4	Hypertension (High Blood Pressure) 01/2023 - 05/2003
4	Stroke (Strokes) 01/2021 - 02/2016
3	Pathologic Constriction (Stenosis) 01/2022 - 09/2004
3	Thrombosis (Thrombus) 01/2022 - 01/2014
3	Coronary Artery Disease (Coronary Atherosclerosis) 12/2016 - 08/2004
2	Fibrosis (Cirrhosis) 01/2023 - 01/2022
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2005
2	Infections 12/2017 - 11/2017
2	Necrosis 12/2016 - 02/2016
2	Obesity 03/2015 - 04/2011
2	Insulin Resistance 03/2015 - 04/2011
2	Body Weight (Weight, Body) 01/2012 - 09/2011
2	Infarction (Infarctions) 06/2011 - 04/2006
2	Hyperplasia 05/2009 - 09/2004
2	Stable Angina 08/2004 - 08/2003
1	Myocarditis (Carditis) 01/2023
1	Cardiac Arrhythmias (Arrythmia) 01/2022
1	Abdominal Aortic Aneurysm 01/2022
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2022
1	Ischemic Stroke 01/2020
1	Autoimmune Diseases (Autoimmune Disease) 11/2017
1	Chest Pain (Chest Pains) 12/2016
1	Ischemia 12/2016
1	Weight Gain 03/2015
1	Fatty Liver 03/2015
1	Peripheral Vascular Diseases (Peripheral Vascular Disease) 01/2014

Drug/Important Bio-Agent (IBA)

17	Apolipoproteins E (ApoE)IBA 01/2022 - 08/2006
11	CytokinesIBA 01/2018 - 12/2003
9	LipidsIBA 01/2022 - 11/2008
7	ApolipoproteinsIBA 01/2021 - 08/2006
6	Immunoglobulin M (IgM)IBA 01/2023 - 09/2011
5	Transforming Growth Factor beta (TGF-beta)IBA 08/2006 - 06/2002
4	Immunoglobulin G (IgG)IBA 01/2023 - 02/2017
4	Proteins (Proteins, Gene)FDA Link 01/2023 - 02/2011
4	CholesterolIBA 01/2022 - 10/2006
4	Monoclonal AntibodiesIBA 01/2022 - 01/2013
4	CollagenIBA 09/2011 - 09/2004
4	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2009 - 12/2003
3	Angiotensin IIIBA 01/2023 - 07/2004
3	PerforinIBA 01/2022 - 03/2013
3	Immunoglobulins (Immunoglobulin)IBA 01/2021 - 01/2018
3	B-Cell Activation Factor ReceptorIBA 02/2017 - 01/2012
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 02/2017 - 11/2008
3	HMGB1 Protein (HMG1)IBA 11/2015 - 02/2011
3	Superoxides (Superoxide)IBA 09/2004 - 12/2002
2	oxidized low density lipoproteinIBA 02/2017 - 11/2016
2	Biomarkers (Surrogate Marker)IBA 12/2016 - 01/2014
2	AllergensIBA 02/2016 - 02/2012
2	Interleukin-6 (Interleukin 6)IBA 03/2015 - 08/2004
2	Granzymes (Granzyme)IBA 04/2014 - 03/2013
2	AntibodiesIBA 04/2014 - 01/2013
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2013 - 08/2004
2	Neutralizing AntibodiesIBA 02/2011 - 01/2006
2	C-Reactive ProteinIBA 07/2009 - 08/2004
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 11/2008 - 04/2004
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 05/2007 - 06/2002
2	AnionsIBA 09/2004 - 04/2004
2	Endothelin-1 (Endothelin 1)IBA 08/2004 - 02/2004
1	Interferon Regulatory FactorsIBA 01/2023
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023
1	VaccinesIBA 01/2023
1	Proteasome InhibitorsIBA 01/2023
1	Bortezomib (Velcade)FDA Link 01/2023
1	Immunoglobulin IsotypesIBA 01/2023
1	Immune Checkpoint InhibitorsIBA 01/2023
1	mRNA VaccinesIBA 01/2023
1	Antiviral Agents (Antivirals)IBA 01/2023
1	Phenobarbital (Luminal)FDA Link 01/2022
1	CyclodextrinsIBA 01/2022
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2022
1	Factor XIIa (Coagulation Factor XIIa)IBA 01/2022
1	AlarminsIBA 01/2021
1	AutoantibodiesIBA 01/2021
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2021
1	Cytotoxins (Cytolysins)IBA 11/2017
1	ChemokinesIBA 11/2017
1	Therapeutic UsesIBA 02/2017
1	Evans Blue (Blue, Evans)FDA Link 12/2016
1	Troponin IIBA 12/2016
1	Fatty Acid-Binding ProteinsIBA 12/2016
1	Fatty Acid Binding Protein 3IBA 12/2016
1	phosphorylethanolamine (phosphoethanolamine)IBA 02/2016
1	tesmilifene (DPPE)IBA 02/2016
1	Liposomes (Liposome)IBA 06/2015
1	PhosphatidylserinesIBA 06/2015
1	P-SelectinIBA 01/2014
1	SelectinsIBA 01/2014
1	Diphtheria ToxinIBA 01/2014

Therapy/Procedure

8	Therapeutics 01/2023 - 09/2011
2	Immunotherapy 01/2023 - 11/2017
2	Splenectomy 01/2018 - 06/2015
1	Ligation 01/2022
1	Precision Medicine 01/2022
1	Immunomodulation 12/2017